How to run a python script using Jira automation rule without using any third party software

[DIPAYANGANGULY]

I am trying to run a python script using Jira automation rule without using any third party  software like bitbucket, aws , azure etc. Is there any way to do that? 

Also is there any steps available for connecting Jira software(cloud) with microsoft power automate.

[Pavlomir Marinov-DevAcrobats-]

Greetings DIPAYANGANGULY,

Code writing is not my specialty, but I can think of possible solution. 

You can use REST API calls to Jira in order to check if a given condition occurred in order to trigger the execution of your Python code.

Learn more about Rest API from the official page: JIRA Cloud REST API Reference (atlassian.com)